Recurrent Pyroglutamic Acidosis Related to Therapeutic Acetaminophen The American Journal of the Medical Sciences Hepsin as a potential therapeutic target for alleviating acetaminophen induced hepatotoxicity via gap junction regulation and oxidative stress modulation Cell Biology and Toxicology Springer Nature Link g glutamyl cycle. Depletion of glutathione by acetaminophen leads to Download Scientific Diagram Acetaminophen, also known as Tylenol, is used to help with pain & to reduce fever. However, taking too much acetaminophen can be harmful to the liver which filters out toxins &