Copper Peptide Side Effects: What to Know Before You Start HealthyDerm Some people notice their skin looks worse before it improves with GHK Cu. This temporary phase is often called the copper uglies., #skincare, #ghkcu, #skinhealth, #longevity, #peptides GHK Cu (copper peptide) used topically is one of the most well studied skin repair peptides. Here's how it helps the skin, in practical terms: 1. Boosts collagen & elastin GHK Cu signals your skin GHK Cu Cream Benefits & Top Picks 2025