L Carnitine as an off label use for VALPROIC ACID TOXICITY HOW AND WHY? Valproic acid may interrupt fatty acid metabolism, impairing mitochondrial function and ultimately urea metabolism, leading to Raghad Altelly Carnitine: Genetic Variants Affecting Mitochondrial Energy and Health Effect of lactulose, L carnitine, ALA and the combined dose of Download Scientific Diagram Mitochondrial targets in hyperammonemia: Addressing urea cycle function to improve drug therapies ScienceDirect
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l-carnitine and ammonia levels Reversible weakness and encephalopathy while on long-term valproate treatment due to carnitine deficiency