Can B12 Make You Nauseous? The Stylus B12 Injections and IV Infusion Treatments to Boost Your Vitality High dose vitamin B12 supplements can sometimes cause side effects, including headache, nausea, vomiting, mild diarrhea, itching, skin rash, tiredness, weakness, or tingling in the hands and feet. OC: Signs You May Have a B12 Deficiency
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