ECTOPIC trial: The efficacy of flEcainide Compared To metOprolol in reducing Premature ventrIcular Contractions: A randomized open label crossover study in pediatric patients Heart Rhythm Management of Premature Ventricular Complexes in the Outpatient Setting Mayo Clinic Proceedings Effect of Flecainide in Idiopathic Premature Ventricular Contractions and the Induced CardiomyopathyUNIFLECA: A Single Arm, Non Randomized Trial: Review of the Literature and Initial Results Premature ventricular contractions (PVCs): Explained , PVCs are abnormal heartbeats that occur early on (prematurely) in the cardiac cycle. They originate in the ventricles (hence the name!) ,