Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Glutathione & Diabetes: How the Body's Master Antioxidant Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification Summary. Depletion of glutathione (GSH) and increased ROS production Download Scientific Diagram