Biologic and Small Molecule Therapies for Moderate to Severe Psoriasis: Focus on Psoriasis Comorbidities BioDrugs Springer Nature Link Many treatment guidelines for psoriasis rely heavily on body surface area (BSA) involvement to determine disease severity and eligibility for systemic therapies like biologics. Traditionally, patients with less than 10% BSA involvementespecially Signaling pathways and targeted therapies for psoriasis Signal Transduction and Targeted Therapy Inflammatory memory in psoriasis: From remission to recurrence Journal of Allergy and Clinical Immunology