Gut microbe derived metabolite trimethylamine N oxide activates PERK to drive fibrogenic mesenchymal differentiation: iScience Trimethylamine N oxide (TMAO) is a small molecule produced in humans primarily by the gut liver axis and has become an important biomarker, and possible mediator, of cardiometabolic and renal disease. Dietary choline, phosphatidylcholine ( Emerging role of trimethylamine N oxide (TMAO) in colorectal cancer Applied Microbiology and Biotechnology Springer Nature Link Dietary allicin reduces transformation of L carnitine to TMAO through impact on gut microbiota ScienceDirect
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tmao l-carnitine TMAO: Why It Increases & Factors That May Reduce TMAO levels