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napqi and glutathione Mechanisms of Hepatocyte Detoxification
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napqi and glutathione Mechanisms of Hepatocyte Detoxification
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Napqi hi res stock photography and images Alamy Problem 2: N acetyl para benzoquinone (NAPQI) is an oxidized metabolite of acetaminophen formed in the liver. NAPQI is converted into an acetaminophen glutathione conjugate, a non toxic metabolite Metabolic pathway for NAPQI formation and detoxification by conjugation Download Scientific Diagram GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY
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napqi and glutathione Mechanisms of Hepatocyte Detoxification
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