Glutathione peroxidase Wikipedia Biochemistry Class notes: RBC Metabolism (Part 2) : Mechanisms of preventing oxidative denaturation of hemoglobin GSH synthesis in the human RBC. The metabolite labels denote: Cys, Download Scientific Diagram In G6PD deficiency (XR), we have increased oxidative damage to RBCs, leading to intravascular hemolysis with decreased serum haptoglobin. We have decreased NADPH production, which means decreased conversion of oxidized ( S S ) glutathione
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