Lip Pigmentation Treatment in Singapore Figure 9 from Pigmented lesions of the oral cavity: review, differential diagnosis, and case presentations. Semantic Scholar Definition of melanocytic macules associated with Peutz Jeghers syndrome NCI Dictionary of Genetics Terms NCI Mara Ever wondered what those little brown spots are that are often found on the lip? Many refer to them as a freckle but the medical term is melanotic macules.