Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Tylenol's Impact on Glutathione and Liver Damage Tylenol is just poison. , Dr. Stanton Hom explains how a simple over the counter drug can deplete glutathione, dysregulate detox, and show up in the literature as a risk factor for autism, asthma, Tylenol and Glutathione: Myths Debunked